Thompson injured his groin during last week's 1-0 win over Luton Town and the midfielder has been undergoing treatment all week in a hope for him to play against Danny Wilson's side.
Dennis Wise will be without the services of Jonathon Douglas as he is with the Republic of Ireland squad.
Douglas has been called up by Steve Staunton for the Republic's Euro 2008 qualifiers against Slovakia and the Czech Republic.
Jonny Howson and Andy Hughes are in contention for central roles and Ian Westlake is ready for a comeback after two weeks out through injury.
Recent signing Paul Huntington is likely to be named on the bench but goalkeeper Alan Martin, who joined Leeds from Motherwell on the final day of the transfer window, has been named in Scotland's U-19 squad and will not be available.
The Whites (from): Ankergren, Richardson, Gardner, Heath, Marques, Huntington, Hughes, Clapham, Parker, Prutton, Thompson, Carole, Westlake, Howson, Bayly, Delph, Weston, Beckford, Kandol, Ameobi.